Fertility

Egg Donation

Egg donation is a remarkable process that enables women who are unable to conceive naturally to achieve pregnancy with the help of another woman's eggs.
Egg Donation

Overview

Egg donation is a process where a woman, known as the donor, provides her eggs to another woman, the recipient, to help her conceive a child. This procedure is often part of assisted reproductive technologies like in vitro fertilization (IVF).

About Egg Donation

Egg donation is a remarkable process that enables women who are unable to conceive naturally to achieve pregnancy with the help of another woman's eggs. This procedure is a cornerstone of assisted reproductive technologies, such as in vitro fertilization (IVF). It involves a donor who undergoes medical and psychological evaluations to ensure her health and suitability. Following this, the donor takes medications to stimulate her ovaries to produce multiple eggs, which are then retrieved through a minor surgical procedure. These eggs are fertilized with sperm in a lab, and the resulting embryos are transferred to the recipient's uterus. Egg donation provides a pathway to parenthood for many individuals and couples facing infertility challenges, offering hope and the possibility of starting or expanding their families.

What is Egg donation? 

Egg donation is a vital and transformative process within the realm of assisted reproductive technologies, offering hope to individuals and couples facing infertility challenges. This procedure involves a woman, known as the egg donor, who voluntarily provides her eggs to another woman, the recipient, to help her conceive a child. The steps of egg donation include:

  • The journey begins with the donor undergoing a comprehensive medical and psychological screening to ensure she is in good health and suitable for donation. This screening process is crucial as it helps to minimize any potential risks to both the donor and the recipient.

  • Once the donor is deemed suitable, she begins a regimen of medications designed to stimulate her ovaries to produce multiple eggs in a single cycle. This phase, known as ovarian stimulation, typically lasts for about 10 to 14 days and involves regular monitoring through blood tests and ultrasounds to track the development of the eggs. The goal is to produce a sufficient number of mature eggs that can be retrieved for fertilization.

  • The egg retrieval process is a minor surgical procedure performed under sedation. Using ultrasound guidance, a thin needle is inserted through the vaginal wall to reach the ovaries and gently aspirate the eggs from the follicles. This procedure usually takes about 20 to 30 minutes, and the donor can typically return to normal activities within a day or two.

  • Once the eggs are retrieved, they are fertilized with sperm in a laboratory setting to create embryos. This fertilization process can be done using the recipient's partner's sperm or donor sperm, depending on the specific circumstances. The resulting embryos are then cultured for a few days before being transferred to the recipient's uterus. The recipient may undergo hormonal treatments to prepare her uterine lining for implantation and to support early pregnancy.

Egg donation is a highly regulated process, with strict guidelines and protocols in place to ensure the safety and well-being of both the donor and the recipient. It provides a valuable option for women who are unable to conceive with their own eggs due to various reasons, such as advanced maternal age, premature ovarian failure, genetic disorders, or previous medical treatments like chemotherapy. For many, egg donation represents a beacon of hope, offering the possibility of achieving pregnancy and building a family.

Who needs Egg Donation? 

Candidates for using donated eggs typically include women and couples facing specific fertility challenges that prevent them from conceiving with their own eggs, as well as same-sex couples. Candidates include:

  • One primary group consists of women experiencing diminished ovarian reserve, a condition where the quantity and quality of their eggs are significantly reduced. This can be due to advanced maternal age, where natural egg production declines, or premature ovarian failure, which affects about 1% of women under 40. Women who have undergone treatments like chemotherapy or radiation, which can damage the ovaries, are also prime candidates for egg donation. Additionally, women with genetic disorders that they do not wish to pass on to their offspring may opt for donor eggs to ensure the health of their future children.

  • Another group includes women who have had multiple unsuccessful IVF cycles with their own eggs. These women may have a normal uterus but face challenges with egg quality or quantity, making it difficult to produce viable embryos. For these individuals, using donor eggs can significantly increase the chances of a successful pregnancy. Similarly, women who have had previous ovarian surgeries that have impacted their ovarian function may turn to egg donation as a viable option.

  • Men pursuing surrogacy also form a distinct category of candidates for egg donation. Single men or same-sex male couples who wish to have biological children often rely on egg donors and gestational carriers to achieve parenthood. This process allows them to have a genetic link to their child while utilizing the reproductive capabilities of a surrogate.

  • Egg donation is also considered by women who have non-functioning ovaries due to conditions like Turner syndrome or other congenital anomalies. These women may have a normal uterus but lack the ability to produce eggs, making donor eggs their best option for achieving pregnancy.

Overall, the decision to use donor eggs is often made after careful consideration and consultation with fertility specialists. It involves understanding the medical, emotional, and ethical implications of the process. For many, egg donation represents a beacon of hope, offering the possibility of experiencing pregnancy and parenthood despite significant fertility challenges. 

About Egg Donation
About Egg Donation
About Egg Donation
About Egg Donation

Egg Donation Procedure

Who can donate their eggs?

Egg donation is a generous act that requires donors to meet specific criteria to ensure the safety and success of the process. Potential egg donors are typically women between the ages of 21 and 31, as this age range is associated with higher egg quality and better responses to fertility medications. Donors must be in good physical health, which includes having a body mass index (BMI) within a healthy range, usually between 19 and 29. Regular, monthly menstrual cycles are also essential, as they indicate normal ovarian function. An egg donor is required:

  • A thorough medical history is crucial for potential donors. They must have no significant genetic disorders or inheritable conditions in their family history. Additionally, donors should be free from infectious diseases such as HIV and hepatitis C. Psychological health is equally important; donors must be mentally stable and free from any history of substance abuse or use of psychoactive drugs.

  • Lifestyle factors play a significant role in determining eligibility. Donors must be non-smokers and should not use illicit drugs or cannabis products. They should also not be using certain forms of birth control, such as Depo-Provera injections or contraceptive implants, as these can interfere with the egg retrieval process. Furthermore, donors must be willing and able to self-administer hormonal injections required for ovarian stimulation.

  • The screening process for egg donors is rigorous and includes medical examinations, blood tests, and ultrasounds to assess ovarian function and overall health. Psychological evaluations are conducted to ensure that donors are emotionally prepared for the process and understand the implications of their donation. Donors must also be dependable, responsible, and able to commit to the time and appointments required for the donation process.

  • In addition to these medical and lifestyle criteria, egg donors should have a supportive network, such as a partner, friend, or family member, to help them through the process. This support can be crucial for managing the physical and emotional demands of egg donation.

Overall, egg donation is a deeply altruistic act that requires careful consideration and a commitment to helping others. The generosity of egg donors has a profound impact, offering hope and the possibility of building a family for those in need.

The process of egg donation

The process of egg donation is a detailed and carefully regulated procedure designed to ensure the safety and success of both the donor and the recipient. It begins with the selection and screening of potential egg donors. Women who wish to donate their eggs typically undergo a comprehensive medical and psychological evaluation to ensure they are healthy and suitable for the process. This includes a thorough review of their medical history, genetic screening, and tests for infectious diseases. The process includes:

  • Once a donor is approved, she starts a regimen of hormonal medications to stimulate her ovaries to produce multiple eggs in one cycle. This phase, known as ovarian stimulation, involves daily injections of hormones such as follicle-stimulating hormone (FSH) and luteinizing hormone (LH) for about 10 to 14 days. During this period, the donor is closely monitored through blood tests and ultrasounds to track the development of the eggs and adjust medication dosages as needed.

  • When the eggs are deemed mature, the donor receives a final injection of human chorionic gonadotropin (hCG), often referred to as the "trigger shot”, to prepare the eggs for retrieval. The egg retrieval procedure is performed approximately 36 hours after the trigger shot. This minor surgical procedure is done under sedation and involves using a thin needle, guided by ultrasound, to aspirate the eggs from the ovarian follicles through the vaginal wall. The procedure typically takes about 20 to 30 minutes, and the donor can usually resume normal activities within a day or two.

  • After retrieval, the eggs are immediately evaluated and fertilized with sperm in a laboratory setting to create embryos. This fertilization process can involve the recipient's partner's sperm or donor sperm, depending on the circumstances. The resulting embryos are cultured for a few days before being transferred to the recipient's uterus. The recipient may undergo hormonal treatments to prepare her uterine lining for implantation and to support early pregnancy.

Throughout the egg donation process, both the donor and the recipient receive extensive support and counseling to address any medical, emotional, or ethical concerns. The entire process, from initial screening to egg retrieval, typically spans about two months. Egg donation is a highly regulated and altruistic act that provides a valuable opportunity for individuals and couples struggling with infertility to achieve their dream of parenthood. 

The risks of the donated egg method

Egg donation, while generally safe, carries certain risks and potential side effects that both donors and recipients should be aware of. These risks include:

  • One of the primary risks associated with egg donation is Ovarian Hyperstimulation Syndrome (OHSS), a condition that can occur when the ovaries are overstimulated by fertility medications. OHSS can cause symptoms ranging from mild abdominal pain and bloating to more severe complications like fluid accumulation in the abdomen and chest, blood clots, and kidney failure. In rare cases, OHSS can be life-threatening and may require hospitalization.

  • Another risk is ovarian torsion, where an ovary twists around the ligaments that hold it in place, potentially cutting off its blood supply. This condition is painful and typically requires surgical intervention. Additionally, the egg retrieval procedure itself, which involves inserting a needle through the vaginal wall to aspirate the eggs, carries risks such as bleeding, infection, and damage to surrounding organs.

  • The medications used in the egg donation process can also have side effects. Common side effects include hot flashes, mood swings, headaches, and bloating. Some donors may experience more severe reactions, such as allergic responses to the medications or complications from the anesthesia used during the egg retrieval procedure. There is also a small risk of developing ovarian cysts or experiencing a temporary loss of fertility following the donation.

  • Long-term risks of egg donation are still being studied, but there is some concern about the potential impact on a donor's future fertility and overall health. While most studies have not found a significant increase in long-term health risks, the lack of comprehensive, long-term data means that these potential risks cannot be entirely ruled out.

  • For recipients, the primary risks are related to the IVF process itself, including the possibility of multiple pregnancies, which can increase the risk of complications such as preterm birth and low birth weight. There is also a small risk of birth defects, similar to those seen in natural pregnancies.

Despite these risks, egg donation remains a valuable option for many individuals and couples struggling with infertility. Both donors and recipients need to undergo thorough medical evaluations and to be fully informed about the potential risks and benefits before proceeding with the process. 

Egg Donation in Iran

Equipped hospitals, and advanced specialized centers with experienced doctors and specialists are available in all medical treatment areas in Iran. Also, good hotels and entertainment centers have made Iran an appropriate choice for patients who are struggling with getting pregnant and need Egg Donation.

Is Egg Donation Allowed in Iran?

Is Egg Donation Allowed in Iran?

Egg donation is indeed allowed in Iran and is regulated by the Ministry of Health and Medical Education. The process is legal and widely accepted, making Iran a notable destination for fertility treatments, including egg donation. The legal framework in Iran is influenced by Islamic principles, and the practice is generally considered permissible (halal) under Shia Islamic law, although it requires a religious fatwa to proceed. This flexibility in Shia jurisprudence contrasts with some Sunni interpretations, which may be more restrictive regarding third-party involvement in reproduction.

In Iran, egg donation is a well-established procedure, and the country has developed a robust system to support it. The process involves thorough medical and psychological evaluations of potential donors to ensure they are healthy and mentally prepared for the donation. Donors are typically young, healthy women who undergo hormonal stimulation to produce multiple eggs, which are then retrieved through a minor surgical procedure. These eggs are fertilized with sperm in a laboratory, and the resulting embryos are transferred to the recipient's uterus. Egg donation in Iran also offers the option of anonymity or known donation, depending on the preferences of the donor and the recipient. This flexibility allows for a more personalized approach to the donation process, catering to the specific needs and wishes of the involved parties. Additionally, donors are compensated for their time and effort, although the exact amount can vary.

Egg Donation Success Rate in Iran

Egg Donation Success Rate in Iran

Egg donation in Iran boasts impressive success rates, making it a highly sought-after option for individuals and couples facing infertility challenges. The success rates for egg donation in Iran typically range between 50% and 60%, which is comparable to some of the best fertility centers worldwide. These high success rates are attributed to several factors, including the meticulous selection of egg donors, advanced medical technologies, and personalized patient care.

The process begins with the careful screening of potential egg donors. Donors undergo rigorous medical and psychological evaluations to ensure they are healthy and suitable for the donation process. This thorough screening helps to minimize risks and maximize the chances of successful fertilization and implantation. Additionally, the use of advanced hormonal stimulation protocols ensures that a sufficient number of high-quality eggs are retrieved from the donors.

Iranian fertility clinics are equipped with state-of-the-art technology and staffed by experienced specialists who are well-versed in the latest assisted reproductive techniques. These clinics follow strict protocols to optimize every step of the egg donation process, from ovarian stimulation and egg retrieval to fertilization and embryo transfer. The use of cutting-edge laboratory techniques, such as intracytoplasmic sperm injection (ICSI) and preimplantation genetic testing (PGT), further enhances success rates by ensuring that only the healthiest embryos are selected for transfer.

Egg Donation Cost in Iran

Egg Donation Cost in Iran

The cost of egg donation in Iran is relatively affordable compared to many Western countries, making it an attractive option for individuals and couples seeking fertility treatments. On average, the cost of egg donation in Iran ranges between 3500-4500 USD. This price typically includes various components of the treatment process, such as the cost of the donated eggs, ultrasounds, blood tests for both the donor and the recipient, sperm analysis, medications, in vitro fertilization (IVF), and the embryo transfer to the recipient's uterus. 

Several factors contribute to the overall cost of egg donation in Iran. The choice of clinic and its location can influence the price, as some clinics may offer more advanced facilities and experienced specialists, which can come at a higher cost. Additionally, the type of egg donation procedure, whether it involves fresh or frozen eggs, can also affect the total expense. Fresh egg donation cycles tend to be more expensive due to the synchronization required between the donor and the recipient's cycles.

The affordability of egg donation in Iran, combined with the high success rates and quality of care, makes it an appealing option for many individuals and couples facing infertility challenges. By choosing to undergo egg donation in Iran, patients can access cutting-edge fertility treatments without the financial burden often associated with such procedures in other countries. This accessibility allows more people to pursue their dream of parenthood, making egg donation in Iran a life-changing and viable solution for those in need.

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FAQs

To become an egg donor, you typically need to be between the ages of 21 and 31, have a healthy body mass index (BMI) within the range of 19 to 29, have regular menstrual cycles, be in good physical and psychological health, have no significant genetic disorders or inheritable conditions in your family history, be a non-smoker and free from substance abuse, and be willing to undergo medical and psychological evaluations and commit to the time required for the donation process.

Ovarian Hyperstimulation Syndrome (OHSS), ovarian torsion, effects from medications, as well as risks from the egg retrieval procedure.

The egg donation process involves several steps: Screening and Selection, Ovarian Stimulation, Egg Retrieval, and finally Fertilization and Transfer.

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